Fig. 2: KDM4A-AS1 depletion affects phenotype in LNCaP-AI and C4-2 cells.

A, B KDM4A-AS1 knockdown efficiency in LNCaP-AI and C4-2 cell lines. Repeated three times with three biological replicates each time. C, D Validation of cell viability change after KDM4A-AS1 depletion by MTT in LNCaP-AI and C4-2 cell lines. Repeated three times with six biological replicates each time. E, F Validation of cell migration ability after KDM4A-AS1 depletion by transwell assay in LNCaP-AI and C4-2 cell line. Barplots represent the cell count of the corresponding cell line. Repeated three times with three biological replicates each time. G, H Validation of cell proliferation ability after KDM4A-AS1 depletion by colony formation assay in LNCaP-AI and C4-2 cell line. Barplots represent the colony count of the proliferation ability of the corresponding cell lines. Repeated three times with three biological replicates each time.