Fig. 2: Increased miR-371b-5p expression inhibits TNBC growth in vivo. | Oncogene

Fig. 2: Increased miR-371b-5p expression inhibits TNBC growth in vivo.

From: Reduced miR-371b-5p expression drives tumor progression via CSDE1/RAC1 regulation in triple-negative breast cancer

Fig. 2

A Relative expression of miR-371b-5p in MCF10A, MDA-MB-231, and MDA-MB-231/A cells. Data are presented as mean ± SD with 3 technical replicates. B The images of tumors from xenograft mice (miR-control and miR-371b-5p). Xenograft experiment has been conducted with MDA-MB-231/Adaptation cells (MDA-MB-231/A) C Relative miR-371b-5p expression in control tumors and tumors with stably upregulated miR-371b-5p expression in xenograft mice. D and E Comparison of tumor volume and weight between miR-control group and miR-371b-5p group. F Representative immunohistochemistry (IHC) images of Ki67 staining in paraffin-embedded sections from xenograft mice. G The bar graph illustrates Ki67-positive cells in each xenograft group. Scale bar: 100 μm. C–E, G Data are presented as mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.005. Images are representative of each experiment.

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