Table 1 Demographic and clinical details of subjects in each study.

From: Meta-analysis of mucosal microbiota reveals universal microbial signatures and dysbiosis in gastric carcinogenesis

Study

Characteristics

SG (n = 304)

AG (n = 122)

IM (n = 149)

GC (n = 250)

p-value

Coker_2018 (Chinese)

Sample size (n = 311)

110

117

45

39

 

Age

49.6 (10.9)

53.9 (14.0)

54.4 (10.3)

59.9 (10.7)

<0.001

Gender

     

Male

56 (50.9%)

62 (53.0%)

15 (33.3%)

28 (71.8%)

0.006

Female

54 (49.1%)

55 (47.0%)

30 (66.7%)

11 (28.2%)

 

H. pylori status

     

Positive

81 (73.6%)

82 (70.1%)

27 (60.0%)

27 (69.2%)

0.42

Negative

29 (26.4%)

35 (29.9%)

18 (40.0%)

12 (30.8%)

 

Sung_2019 (Chinese)

Sample size (n = 202)

103

5

94

–

 

Age

52.1 (8.3)

52.6 (7.5)

52.6 (8.2)

–

0.819

Gender

     

Male

53 (51.5%)

1 (20.0%)

51 (54.3%)

–

0.359

Female

50 (48.5%)

4 (80.0%)

43 (45.7%)

–

 

H. pylori status

     

Positive

103 (100%)

5 (100%)

94 (100%)

–

NA

Negative

0 (0%)

0 (0%)

0 (0%)

–

 

Ferreira_2018 (Portuguese)

Sample size (n = 135)

81

–

–

54

 

Age

43.6 (7.0)

–

–

58.8 (13.2)

<0.001

Gender

     

Male

79 (97.5%)

–

–

32 (59.3%)

<0.001

Female

2 (2.5%)

–

–

22 (40.7%)

 

H. pylori status

     

Positive

80 (98.8%)

–

–

47 (87.0%)

0.007

Negative

1 (1.2%)

–

–

7 (13.0%)

 

Yu_2017 (Chinese: 80 Mexican: 54)

Sample size (n = 134)

  

134

 

Age

   

61.8 (10.6)

NA

Gender

     

Male

–

–

–

92 (68.7%)

NA

Female

–

–

–

42 (31.3%)

 

H. pylori status

     

Positive

–

–

–

80 (59.7%)

NA

Negative

–

–

–

54 (40.3%)

 

Eun_2014 (Korean)

Sample size (n = 31)

10

–

10

11

 

Age

50.4 (11.5)

–

57.5 (7.3)

65.7 (11.3)

0.019

Gender

     

Male

4 (40.0%)

–

7 (70.0%)

6 (54.5%)

0.445

Female

6 (60.0%)

–

3 (30.0%)

5 (45.5%)

 

H. pylori status

     

Positive

7 (70.0%)

–

4 (40.0%)

7 (63.6%)

0.433

Negative

3 (30.0%)

–

6 (60.0%)

4 (36.4%)

 

Castano- Rodriguez_ 2017 (Malaysian)

Sample size (n = 12)

–

–

–

12

 

Age

–

–

–

62.1 (13.8)

NA

Gender

     

Male

–

–

–

4 (33.3%)

NA

Female

–

–

–

8 (66.7%)

 

H. pylori status

     

Positive

–

–

–

11 (91.7%)

NA

Negative

–

–

–

1 (8.3%)

 
  1. Age format: mean (standard deviation). Kruskal-Wallis test was performed on continuous factor age for getting the p-values. Fisher’s exact test was performed on categorical factors gender and H. pylori status for obtaining the p-values.
  2. SG superficial gastritis, AG atrophic gastritis, IM intestinal metaplasia, GC gastric cancer, NA not applicable.
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