Table 2 Univariate and multivariate Cox regression analysis of overall survival in 126 HCC patients.

From: ANKFN1 plays both protumorigenic and metastatic roles in hepatocellular carcinoma

 

Overall survival

Variables

HR

95% CI

P value

Univariate analysis

 Age

0.795

0.457–1.384

0.417

 Gender

0.445

0.176–1.120

0.086

 Tumor size

1.201

0.692–2.083

0.515

 AFP (ng/mL,≤20/>20)

1.381

0.780–2.447

0.268

 Cirrhosis

2.429

1.370–4.308

0.002**

 Edmondson’s grade

1.578

1.024–2.433

0.039*

 HBV

0.436

0.203–0.938

0.034

 ANKFN1 expression

1.79

1.009–3.175

0.046*

Multivariate analysis

 AFP (ng/mL,≤20/>20)

1.13

0.610–2.093

0.697

 Tumor size

1.094

0.616–1.943

0.76

 Cirrhosis

2.047

1.102–3.800

0.023*

 Edmondson’s grade

0.716

0.323–1.587

0.411

 HBV

0.447

0.197–1.012

0.053

 ANKFN1 expression

2.691

1.199–6.039

0.016*

  1. CI confidence interval, HR hazard ratio, HCC hepatocellular carcinoma.
  2. *P < 0.05. **P < 0.01.
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