Oncogene

Table 2 IGSF9 mutations in breast cancer carcinomas.

From: Immunoglobulin superfamily 9 (IGSF9) is trans-activated by p53, inhibits breast cancer metastasis via FAK

Study	Sample ID	Cancer Type	Protein Change	Functional Impact	Mutation Type	Copy#	Mut in Sample#
INSERM, PLoS Med 2016	MBC-29	Invasive Breast Carcinoma	R198Q	Deleterious	Missense	Gain	345
TCGA, PanCancer Atlas	TCGA-A2-A3Y0-01	Breast Invasive Ductal Carcinoma	R434P	Deleterious	Missense	Gain	147
TCGA, PanCancer Atlas	TCGA-AC-A23H-01	Breast Invasive Ductal Carcinoma	K651N	Tolerated	Missense	Gain	4260
TCGA, PanCancer Atlas	TCGA-AR-A2LE-01	Breast Invasive Lobular Carcinoma	D102Y	Deleterious	Missense	Gain	256
TCGA, PanCancer Atlas	TCGA-D8-A1XK-01	Breast Invasive Ductal Carcinoma	P351Hfs*30	Unknown	FS del	Gain	969
TCGA, PanCancer Atlas	TCGA-AN-A046-01	Breast Invasive Ductal Carcinoma	E934D	Medium	Missense	ShallowDel	5392
TCGA, PanCancer Atlas	TCGA-AN-A046-02	Breast Invasive Ductal Carcinoma	E422*	Unknown	Nonsense	ShallowDel	5392
TCGA, PanCancer Atlas	TCGA-A8-A09Q-01	Breast Invasive Ductal Carcinoma	L289P	Tolerated	Missense	Gain	129
TCGA, PanCancer Atlas	TCGA-A2-A0T5-01	Breast Invasive Ductal Carcinoma	T291P	Deleterious	Missense	Gain	1076
INSERM, PLoS Med 2016	MBC-137	Invasive Breast Carcinoma	W941*	Unknown	Nonsense	Diploid	41
INSERM, PLoS Med 2016	MBC-180	Invasive Breast Carcinoma	Q263*	Unknown	Nonsense	Amp	63
INSERM, PLoS Med 2016	MBC-39	Invasive Breast Carcinoma	V228F	Tolerated	Missense	Gain	94
INSERM, PLoS Med 2016	MBC-189	Invasive Breast Carcinoma	K1122N	Medium	Missense	Gain	935
TCGA, PanCancer Atlas	TCGA-EW-A2FV-01	Breast invasive Carcinoma (NOS)	P953Qfs*34	Unknown	FS del	Gain	3877
TCGA, PanCancer Atlas	TCGA-EW-A2FV-01	Breast invasive Carcinoma (NOS)	D644lfs*109	Unknown	FS del	Gain	3877
TCGA, PanCancer Atlas	TCGA-EW-A2FV-01	Breast invasive Carcinoma (NOS)	S200Afs*23	Unknown	FS del	Gain	3877

*Represents the termination codon.

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