Fig. 5: Rac1b is dispensable during mammary gland development.

A Representative images of whole-mount stained No:4 inguinal mammary glands of 4-, 6-, 8-, and 10-week-old nulliparous Rac1b+/+ and Rac1b−/− mice. B Higher magnification images of distal parts of the ductal tree at locations depicted with red rectangles in (A). C Representative images of whole-mount stained No:4 inguinal mammary glands of Rac1b+/+ and Rac1b−/− mice at developmental stages of early pregnancy (10.5 d.p.c [days post-coitum]), late pregnancy (18 d.p.c.), and lactation (Day 1 d.p.p [days post-partum]). D Representative images of whole-mount stained No:4 inguinal mammary glands of Rac1b+/+ and Rac1b−/− mice at involution stages of 3, 10 and 21 days post-weaning (d.p.w). Scale bars represent 1 cm in (A, C, D) and 1 mm in (B). Images shown are representative of n ≥ 3 mice.