Table 2 CaP cell line models.
From: PTEN-regulated PI3K-p110 and AKT isoform plasticity controls metastatic prostate cancer progression
Model | Species | PTEN | AR | AKTpoSer473, a |
|---|---|---|---|---|
T402 (Pten, Rb-negative) | Mouse | Deleted | + | ++ |
T402[PTEN] | Mouse | + | + | Low (in 3D) |
LNCaPb | Human | del/mut** | + | ++ |
LNCaP[PTEN] | Human | + | + | Low (in 3D) |
22Rv1 | Human | + | H874Y | Low (in 3D) |
22Rv1[shPTEN] | Human | Low | H874Y | + |
