Table 1 Cox proportional hazard regression analyses for overall survival.

From: The Hippo-YAP signaling pathway drives CD24-mediated immune evasion in esophageal squamous cell carcinoma via macrophage phagocytosis

Clinical characteristics

Univariable analysis

Multivariable analysis

HRa (95% CIb)

P value

HR (95% CI)

P value

Age

0.848 (0.581–1.239)

0.395

 

Gender

1.028 (0.696–1.517)

0.890

 

Differentiation

1.579 (1.091–2.284)

0.015

1.613 (1.108–2.351)

0.013

Tumor invasion

2.033 (1.326–3.116)

0.001

1.119 (0.685–1.828)

0.654

Lymph node metastasis

3.556 (2.450–5.163)

<0.001

1.253 (0.656–2.396)

0.494

Distant metastasis

4.084 (2.487–6.708)

<0.001

1.710 (0.983–2.978)

0.058

Clinical stage

4.047 (2.778–5.895)

<0.001

2.509 (1.212–5.195)

0.013

YAP expression

2.272 (1.538–3.358)

<0.001

1.601 (1.059–2.421)

0.026

CD24 expression

2.145 (1.439–3.196)

<0.001

1.723 (1.114–2.595)

0.009

  1. aHazard ratio.
  2. bConfidence interval.
  3. Bold values indicates statistical significance (P < 0.05).
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