Fig. 2: IFNγ induces G0/G1 cell cycle arrest in breast cancer cells. | Oncogene

Fig. 2: IFNγ induces G0/G1 cell cycle arrest in breast cancer cells.

From: Non-canonical deubiquitination of OTUB1 induces IFNγ-mediated cell cycle arrest via regulation of p27 stability

Fig. 2

A MDA-MB-231 and MDA-MB-453 cells were treated with IFNγ (25–100 ng/mL) for 4 d. Cell viability was verified using MTT assay at the indicated time points. B, C IFNγ-treated cells were subjected to cell cycle analysis and related protein expression using FACS and western blotting, respectively. D Representative EdU staining (green) and DAPI (blue) images of MDA-MB-231 cancer cells. Scale bar = 100 μm. Error bars represent mean ± SEM. *P < 0.01 compared to control.

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