Fig. 7: Mechanism diagram of SENP1-induced YBX1 deSUMOyaltion in promoting CRC progression.

SENP1 catalyzes deSUMOylation of YBX1 to promote its affixion and recruitment of DDX5 protein, which contributes to cancer cell proliferation and migration.

SENP1 catalyzes deSUMOylation of YBX1 to promote its affixion and recruitment of DDX5 protein, which contributes to cancer cell proliferation and migration.