Fig. 2: Co-expression network between differential RBPs and RASGs in osteosarcoma. | Oncogene

Fig. 2: Co-expression network between differential RBPs and RASGs in osteosarcoma.

From: KPNA2 promotes osteosarcoma progression by regulating the alternative splicing of DDX3X mediated by YBX1

Fig. 2

A Venn diagram showed the overlap of genes between human RBP genes and differential expression genes (DEGs) associated with osteosarcoma. B Hierarchical clustering heatmap showed the FPKM of the differentially expressed RBPs (DERBPs) in three types of tissues. C The top 10 enriched GO terms (biological process) were illustrated for DERBPs co-expression RASEs (pSAR ≥ 50%) genes among different groups. D Co-expression network showed the important pathways of RASEs regulated by DERBPs. E Box plot showed the FPKM value of three representative DERBPs (LEPR, ADD3, and KPNA2). F Boxplot showed the splicing ratios of clualt5p174302 MCM7, clualt5p196175 GSN, cluir62713 PLK1, and cluir60246 POLG. *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001.

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