Fig. 2: Wnt3a treatment promotes IQGAP3 localization to non-membrane organelles and cell junctions.
From: Wnt target IQGAP3 promotes Wnt signaling via disrupting Axin1-CK1α interaction
A IQGAP3-biotinylated proteins exclusively found in cells treated with L-cells conditioned media (−Wnt3a). Shown are proximity partners with Fold change ≥ 4, p-value ≤ 0.01, node color denote degree distribution, created with Cytoscape. B IQGAP3-biotinylated proteins exclusively found in cells treated with L-Wnt3a cells conditioned media (+Wnt3a). Shown are proximity partners with Fold change ≥ 4, p-value ≤ 0.01, node color denote degree distribution, created with Cytoscape. C ClueGO analysis for Biological Process enrichment of biotinylated protein in HEK293 cells treated with −Wnt3a and +Wnt3a conditioned media. Size denote number of mapped genes and node color denote p-values. D ClueGO analysis for Cellular Compartment enrichment of biotinylated protein in HEK293 cells treated with −Wnt3a and +Wnt3a conditioned media. Size denote number of mapped genes and node color denote p-values.
