Fig. 5: TRIM29 regulates focal adhesion. | Oncogene

Fig. 5: TRIM29 regulates focal adhesion.

From: TRIM29 promotes bladder cancer invasion by regulating the intermediate filament network and focal adhesion

Fig. 5

A–D TRIM29-KO (TKO) reduces ZYX+ focal adhesion sites during UM-UC5 and UM-UC14 bladder cancer spheroid invasion. Magenta: ZYX. Yellow: Actin. Blue: Hoechst 33342+ Nuclei. Scale bar = 10 µm. E Quantitative analysis of ZYX+ focal adhesions (UM-UC5-WT, n = 80; UM-UC5-TKO, n = 51; UM-UC14-WT, n = 33; UM-UC14-TKO, n = 18) or PXN+ focal adhesions (UM-UC5-WT, n = 168; UM-UC5-TKO, n = 194; UM-UC14-WT, n = 261; UM-UC14-TKO, n = 340). Data represent the mean ± STD. *p < 0.05 for t-test.

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