Fig. 7: Evidence of oncogenic FRA1 signaling in multiple cancer types.
From: FRA1 drives melanoma metastasis through an actionable transcriptional network
A Overall survival curve of patients with high or low FRA1 expression in multiple cancer types from TCGA Pan Cancer Atlas dataset. B Correlation between FRA1 expression and expression of AXL, CDK6, FSCN1 in multiple cancer types from TCGA Pan Cancer Atlas dataset. C Correlation between FRA1 expression and expression of AXL, CDK6, FSCN1 in multiple cancer types from Cancer Cell Line Encyclopedia (CCLE) (Data extracted from DepMap). (LIHC: Liver hepatocellular carcinoma. PDAC: Prostate adenocarcinoma. CODA: Colon adenocarcinoma. LUAD: Lung adenocarcinoma. LUSC: Lung squamous cell carcinoma. NSCLC: Non-small cell lung cancer. STAD: Stomach adenocarcinoma. KIRC: Kidney renal clear cell carcinoma. BLCA: Bladder urothelial carcinoma. BRCA: Breast invasive carcinoma. HNSCC: Head and neck squamous cell carcinoma. ESCC: Esophageal carcinoma.).
