Table1 Response to ITF2357 and Doxorubicin in combination of human sarcoma cells lines

From: Histone deacetylase inhibitor ITF2357 leads to apoptosis and enhances doxorubicin cytotoxicity in preclinical models of human sarcoma

  

CI values at

Cell line

Subtype

ED50

ED 75

ED90

HT1080

Fibrosarcoma

0.40

0.04

0.02

SW982

Synovial sarcoma

0.86

0.43

0.30

SW872

Liposarcoma

0.76

0.85

0.96

SaOS2

Osteosarcoma

0.73

0.85

1.04

U2OS

Osteosarcoma

0.64

0.62

1.02

SKLMS

Leiomyosarcoma

0.16

0.09

0.08

A204

Rabdomyosarcoma

0.52

0.51

0.98

3844b

Osteosarcoma

1.08

1.00

0.95

4052

Condrosarcoma

0.98

0.80

0.76

LS1P

Liposarcoma

0.86

0.83

0.84

  1. CI combination index, ED effective dose
Back to article page