Table 2 SNPs effect on the reporter activity of the HPSE gene enhancer
Cell lines | SNP variants (sense) | p value | SNP variants (antisense) | p value |
|---|---|---|---|---|
U226 | A–B | 0.0003 | A–B | 0.006 |
A–C | 0.008 | A–C | 0.004 | |
B–C | 0.04 | B–C | 0.0004 | |
CAG | A–B | NS | A–B | NS |
A–C | 0.01 | A–C | 0.002 | |
B–C | 0.01 | B–C | 0.003 | |
RPMI8226 | A–B | 0.0003 | A–B | 5.8 × 10−6 |
A–C | 0.02 | A–C | 3.8 × 10−7 | |
B–C | 0.0001 | B–C | 0.7 × 10−5 | |
KG-1 | A–B | NS | A–B | 3.1 × 10−6 |
A–C | NS | A–C | 9.1 × 10−7 | |
B–C | NS | B–C | NS | |
REH | A–B | 0.0003 | A–B | NS |
A–C | 0.0005 | A–C | 0.02 | |
B–C | 2.48 × 10−5 | B–C | NS | |
HT-1080 | A–B | 0.001 | A–B | 0.0001 |
A–C | NS | A–C | 9.98 × 10−5 | |
B–C | 0.002 | B–C | NS | |
A459 | A–B | 0.0001 | A–B | NS |
A–C | 0.06 | A–C | 0.03 | |
B–C | 0.0003 | B–C | NS | |
H1229 | A–B | 0.05 | A–B | 0.001 |
A–C | NS | A–C | NS | |
B–C | 0.04 | B–C | 0.004 | |
PC-3 | A–B | 0.0004 | A–B | 0.06 |
A–C | NS | A–C | NS | |
B–C | 0.0003 | B–C | NS |
