Fig. 7: Analysis of nude mouse tumors generated by NIH3T3 cell expression.
From: Vav1 mutations identified in human cancers give rise to different oncogenic phenotypes

a Representative pictures of H&E-stained tumors generated by NIH3T3 cells stably expressing pcDNA3, Vav1, oncVav1, E59K, D517E, and L801P in NOD/SCID mice. b Histogram showing the calculated numbers of Ki-67-positive cells in tumors of NIH3T3 cells stably expressing pcDNA3, Vav1, oncVav1, E59K, D517E, and L801P. The p value for each of these groups compared to the Vav1 group is recorded above each column. c Representative pictures of tumors generated by NIH3T3 cells expressing pcDNA3, oncVav1, E59K, D517E, and L801P stained with anti-Ki-67 antibodies