Fig. 6
Levels of phospho-c-Met and total c-Met in the tumor tissues from mice treated with different combinations of XL-184 and ZnPP. Representative photomicrographs (magnification, x400) showing the immunohistochemical expression (red stain) of the phospho-c-Met (upper panel) and total c-Met (lower panel) in the tumor tissues from each treatment groups as described in Fig. 5. Right, composite score for phospho-c-Met/c-Met analyzed as described in the methods section. The data reflect three different experiments, in which three to four non-overlapping fields of each specimen were examined in blinded manner. Columns, average of composite scores; bars ± S.D. *p < 0.05 compared with vehicle-treated group
