Fig. 2: miR-214-3p suppressed the proliferation, epithelial–mesenchymal transition (EMT) process, and invasion in fibroblast growth factor receptor 1 (FGFR1)-amplified lung cancer cell lines.
From: Reciprocal regulatory mechanism between miR-214-3p and FGFR1 in FGFR1-amplified lung cancer
H1581, DMS114, and HCC95 cell lines were transfected with miR-214-3p mimic or miR-NC. a, b Cell growth was measured by the CCK8 assay and colony assay. c, d Migration and invasion was determined by scratch assay and transwell assay. e Representative images showing the altered morphological characteristics of the cells. f Quantification of EMT markers was measured by western blot. P values were calculated by Student’s t test: *p < 0.05; **p < 0.01; ****p < 0.0001
