Fig. 3: Fibroblast growth factor receptor 1 (FGFR1) is a direct target of miR-214-3p.
From: Reciprocal regulatory mechanism between miR-214-3p and FGFR1 in FGFR1-amplified lung cancer
a Schematic diagram of the predicted binding site of FGFR1 3′-untranslated region (UTR) and miR-214-3p. b, c Western blot and quantitative real-time PCR (qRT-PCR) analyses of FGFR1 expression levels in H1581 and DMS114 cells transfected with miR-NC or miR-214-3p. d–f Luciferase assay of the reporter plasmids including the wild-type and mutant FGFR1 3′-UTR. P values were calculated by Student’s t test. ****p < 0.0001
