Fig. 4: Stable overexpression of miR-876 suppresses in vivo tumor growth.
From: Novel tumor suppressor role of miRNA-876 in cholangiocarcinoma
a Stable overexpression of miR-876 in the KMCH cell line. b Colony formation ability of KMCH cells stably expressing miR-876. c BCL-XL protein expression levels in KMCH cells expressing miR-876. d Stable expression of miR-876 induces apoptosis. e miR-876 expression suppresses in vivo tumor cell growth. f miR-876 suppresses BCL-XL expression in tumor in vivo. g Western blot analysis showing expression of PARP, caspase 3, and PCNA in miR-876-expressing in vivo tumor samples. *p < 0.05
