Fig. 1: High TCL expression correlates with CRC malignancy.

a, b Gene expression levels in human CRC specimens are examined by qPCR and western blotting. c, d TCL expression levels in a panel of CRC cells were examined by qPCR and western. e, f HT-29 cells were exposed to 1% O2 and harvested at indicated time points. TCL expression levels were examined by qPCR and western. Data represent averages of three independent experiments and error bars represent SEM. g Kaplan–Meier plot of survival in patients with high and low TCL expression.