Table 1 Relationship between expression of SOX9 and clinicopathologic characteristics of breast cancer patients.

From: SOX9 interacts with FOXC1 to activate MYC and regulate CDK7 inhibitor sensitivity in triple-negative breast cancer

Variables

Sox9 low (135)

Sox9 high (143)

P-value

No.

%

No.

%

Age

    

0.474

<53 years

70

51.85%

68

47.55%

≥53 years

65

48.15%

75

52.45%

Pathology gradea

    

0.014

Grade 1

22

16.42%

11

7.69%

Grade 2

95

70.90%

99

69.23%

Grade 3

17

12.69%

33

23.08%

T stageb

    

0.038

1

40

30.08%

46

32.17%

2

92

69.17%

88

61.54%

3

1

0.75%

9

6.29%

Nodal statusc

    

0.748

Negative

56

44.09%

62

45.58%

1–3 positive nodes

35

27.56%

36

26.47%

4–9 positive nodes

31

24.40%

29

21.32%

≥10 positive nodes

5

3.94%

9

6.62%

ER statusd

    

<0.0001

Positive

103

81.75%

71

50.35%

Negative

23

18.25%

70

49.65%

PR statuse

    

<0.0001

Positive

88

68.75%

60

42.55%

Negative

40

31.25%

81

57.45%

Her2 statusf

    

0.525

Positive

29

24.17%

36

27.69%

Negative

91

75.83%

94

72.31%

Outcomeg

    

0.085

Death

29

21.64%

44

30.77%

Survival

105

78.36%

99

69.23%

Subtypesh

     

Luminal A

75

64.1%

57

40.43%

0.001

Luminal B

20

17.09%

22

15.60%

 

HER2-positive

6

5.13%

20

14.18%

 

TNBC

16

13.68%

42

29.79%

 
  1. a1 sample of pathology grade status of Sox9 low expression group was missed.
  2. b2 samples of T stage status of Sox9 low and high expression group were missed, respectively.
  3. c8 and 7 samples of nodal status of Sox9 low and high expression group were missed, respectively.
  4. d7 and 2 samples of ER status of Sox9 low and high expression group were missed, respectively.
  5. e7 and 2 samples of PR status of Sox9 low and high expression group were missed, respectively.
  6. f15 and 13 samples of HER2 status of Sox9 low and high expression group were missed, respectively.
  7. g1 sample of outcome status of Sox9 low expression group was missed, respectively.
  8. h18 and 2 samples of subtype status of Sox9 low and high expression group were missed, respectively.