Fig. 6

Differentially expressed genes in HER2-positive and HER2-negative cell lines A–D and in MamBo89HER2stable versus MamBo43HER2labile cells E–G. A, E Biological processes and B, F KEGG pathways with adjusted p-value<0.05, gathering genes >10 and excluding biological processes and pathways with a number of genes >200. C, D Representation of protein-protein interactions among HER2-negative up-regulated C and down-regulated D gene products (STRING, interaction confidence level 0.9, K-means cluster 5). G Representation of protein-protein interactions among MamBo89HER2stable versus MamBo43HER2labile differentially expressed genes (STRING, interaction confidence level 0.9, K-means cluster 3).