Fig. 2: scRNA-seq profiling of the pre-NACT and post-NACT high-grade serous fallopian tube carcinoma samples. | Oncogenesis

Fig. 2: scRNA-seq profiling of the pre-NACT and post-NACT high-grade serous fallopian tube carcinoma samples.

From: The impact of neoadjuvant chemotherapy on the tumor microenvironment in advanced high-grade serous carcinoma

Fig. 2: scRNA-seq profiling of the pre-NACT and post-NACT high-grade serous fallopian tube carcinoma samples.The alternative text for this image may have been generated using AI.

a UMAP plots showing cell groups by color in the pre-NACT and post-NACT sample groups. b UMAP plots showing pre-NACT and post-NACT cells, clustered and color-coded according to the group. c Box plots showing the CNV signals for each cell type. d UMAP plots showing the cell types by color. e Heatmap showing the top marker genes in each cell type. f Histogram indicating the proportion of cell types in each analyzed sample. g Heatmap showing the expression regulation by transcription factors in each cell type, as estimated using SCENIC. UMAP uniform manifold approximation and projection.

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