Fig. 8: TAGLN promotes lung cancer progression via activation of cancer-associated fibroblasts with enhanced IL-6 release. | Oncogenesis

Fig. 8: TAGLN promotes lung cancer progression via activation of cancer-associated fibroblasts with enhanced IL-6 release.

From: Transgelin promotes lung cancer progression via activation of cancer-associated fibroblasts with enhanced IL-6 release

Fig. 8: TAGLN promotes lung cancer progression via activation of cancer-associated fibroblasts with enhanced IL-6 release.

TAGLN promoted the pro-tumor phenotype of fibroblasts and increased their secretion of pro-inflammatory cytokines, such as IL-6, via the activation of the NF-κB signaling pathway which in turn regulates lung cancer cells migration/invasion.

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