Fig. 4: Genes contained in ecDNA. | Oncogenesis

Fig. 4: Genes contained in ecDNA.

From: Circlehunter: a tool to identify extrachromosomal circular DNA from ATAC-Seq data

Fig. 4

A Distribution of genes in ecDNA. B Distribution of recurrent oncogenes contained in ecDNA. C Kernel density estimate of copy number ascending rank between samples within ecDNA contained the oncogene, and those without ecDNA contained the oncogene. D Kernel density estimate of expression level ascending rank between samples within ecDNA contained the oncogene, and those without ecDNA contained the oncogene. E Kernel density estimate of gene effect rank between samples within ecDNA contained the oncogene, and those without ecDNA contained the oncogene. F Histogram of mean copy number for ecDNA-contained gene and gene never contained in any ecDNA. G The fraction of gene mutated in ecDNA-contained gene and gene never contained in any ecDNA.

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