Fig. 6: ecMYC-driven SCLC-N expression pattern. | Oncogenesis

Fig. 6: ecMYC-driven SCLC-N expression pattern.

From: Circlehunter: a tool to identify extrachromosomal circular DNA from ATAC-Seq data

Fig. 6

A GSEA result of term HALLMARK_MYC_TARGETS_V2 from MSigDB between SCLC cell lines with ecMYC and chrMYC. B GO analysis for differentially expressed genes between cell lines with ecMYC and chrMYC. C Heatmap of 4 SCLC subtype factors expression. D Correlation between MYC and NEUROD1 expression levels in SCLC cell lines. E Accessibility of ecMYC and chrMYC cell lines at NEUROD1 TSS. F The methylation level of the CpG cluster in the NEUROD1 locus. G The epigenomic landscape of the NCIH-2171 cell line in NEUROD1 locus.

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