Fig. 7: AIFM2-promoted HCC metastasis through increasing PGC-1α-regulated mitochondrial biogenesis.

A and B Overexpression or knockdown of PGC-1α was examined by qRT-PCR (A) and western blot (B) analysis in HCC cells with indicated treatment. C and D Transwell migration (C) and invasion (D) assays in HCC cells with indicated treatment.