Fig. 7: WDR4 expression positively correlates with DDX20 expression and predicts LN metastasis of bladder cancer.

A Representative images of WDR4 and DDX20 IHC staining in bladder cancer tissues, Scale bar of upper panel = 500 μm, Scale bar of lower panel = 50 μm. B Pearson correlation between WDR4 and DDX20 levels in clinical bladder cancer tissues. AOD of WDR4 (C) and DDX20 (D) in normal bladder tissues and bladder cancer tissues from patients with and without LN metastasis. E Univariate analyses to determine risk factors associated with LN metastasis in bladder cancer patients (n = 77). F Schematic illustration of the mechanism of WDR4 in promoting LN metastasis of bladder cancer.