Fig. 1: Clinical significance of B4GALT1 expression in HCC cells. | Oncogenesis

Fig. 1: Clinical significance of B4GALT1 expression in HCC cells.

From: Decreased B4GALT1 promotes hepatocellular carcinoma cell invasiveness by regulating the laminin-integrin pathway

Fig. 1

A Data from Oncomine indicated the downregulation of B4GALT1 expression in HCC tissue compared with normal liver tissue. Two datasets, Chen Liver and Roessler Liver 2, were analyzed. ***P < 0.001. B Kaplan-Meier (KM) survival analysis for patients with HCC based on the KM plotter and R2 (Genomics Analysis and Visualization Platform) webtools. B4GALT1 in HCC tumors were categorized as low and high expression as indicated. P value was calculated using the log-rank test. C Scoring of B4GALT1 expression determined via immunohistochemistry (IHC). Scale bar, 50 µm. D B4GALT1 expression in HCC tumor (T) and its paired non-tumor liver tissue (N). N > T indicates that B4GALT1 expression in the non-tumor liver tissue is higher than that in the HCC tumor. N ≤ T indicates that B4GALT1 expression in the non-tumor liver tissue is less than or equal to that in the HCC tumor. Representative images are shown. Scale bar, 50 µm. E Kaplan-Meier survival analysis of B4GALT1 expression in HCC tissue from patients. P value was calculated using the log-rank test. Data are represented as mean ± SD. **P < 0.01, Student’s t-test.

Back to article page