Fig. 1: DSRCT CSC gene expression. | Oncogenesis

Fig. 1: DSRCT CSC gene expression.

From: Transcriptomic analysis identifies B-lymphocyte kinase as a therapeutic target for desmoplastic small round cell tumor cancer stem cell-like cells

Fig. 1

A Light microscopy of three DSRCT cell lines grown in adherent or sphere culture conditions (scale bar = 100 µm). B Volcano plots of differentially expressed genes in sphere versus adherent culture (red=significantly upregulated in spheres, blue=significantly upregulated in adherent culture, FDR < 0.05). C Venn diagram of commonly upregulated and downregulated genes between three DSRCT cell lines in sphere versus adherent culture (log2FC > |0.58|, FDR < 0.05). D, E Overrepresentation of sphere-upregulated genes (D) and downregulated genes (E) in GO-BP pathways. F Heatmaps of differentially expressed genes in chromatin assembly and disassembly, cell junction assembly, and positive growth regulation GO-BP pathways (log2FC sphere/adherent gene expression).

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