Table 3 Secondary outcome measures of school-age children
From: Recommendations for the design of therapeutic trials for neonatal seizures
Criteria | Description |
|---|---|
Post-neonatal onset epilepsy | |
Neuromotor outcomes | 1. Gross Motor Function Classification System (GMFCS) 2. Gross Motor Function Measure (GMFM) 3. Movement Assessment Battery for Children (Movement ABC 2)93: 4 to 12 years; targeted to detect gross motor or fine motor impairments 4. Peabody Developmental Motor Scale, revised (PDMS-2)94 |
Cognitive outcomes | 1. British Ability Scale, Third Edition (BAS 3)95: 3 years to 17 years 11 months; Early Years Battery for 3 years to 5 years 11 months 2. Differential Ability Scales Second Edition (DAS-II)96: 3 years 6 months to 17 years 3. Mullen Scale of Early Learning: Birth to 5 years 8 months 4. Stanford-Binet Intelligence Scales, Fifth Edition (SB5)97: 2 years to 85 years a. Wechsler Preschool and Primary Scale of Intelligence—Fourth Edition (WPPSI—IV)98: 2 years 6 months to 7 years 7 months b. Wechsler Intelligence Scale for Children—Fifth Edition (WISC—V)99: 6 years to 16 years 11 months 5. Standardized tests of executive function, which underpin many adverse cognitive outcomes a. NEPSY, Second Edition (NEPSY-II)100 b. Behavior Rating Index of Executive Function, Second Edition (BRIEF2)101 c. Cognitive Assessment System, Second Edition102 6. Behavior and social-emotional problems: many questionnaires/surveys are available for this age group, including the Child Behavior Checklist103, BITSEA104, ITSEA104, and M-CHAT105 7. Academic attainment tests are for school-age children, 6 years and above |