Fig. 3: Transcriptional modular repertoire analysis in children with severe RSV.
From: Gene signature of children with severe respiratory syncytial virus infection
The difference between the proportion of upregulated and downregulated genes in each module when comparing children with severe and mild RSV are indicated in red and green bars, respectively. An increase in the proportion of upregulated genes was observed in modules related to neutrophil (M11.2, M37.1, M132, M163), inflammation (M16, M25, M33, M53), blood coagulation (M11.1), monocytes (M11, M23, M64, M73, M118, M118.1), and platelets (M42) in children in severe RSV. On the other hand, suppression of gene expression was observed in modules related to T cell activation (M7.1, M7.4, M54), and T cell differentiation (M14, M18).
