Table 4 Performance of the model in cohort I and cohort II.

From: The development and validation of a cerebral ultrasound scoring system for infants with hypoxic-ischaemic encephalopathy

Cut-off valuea

≥3

≥4

≥5

≥6

≥7

Cohort I

 Sensitivity

93% (76–99)

79% (60–91)

45% (27–64)

28% (13–47)

17% (7–36)

 Specificity

86% (74–94)

88% (76–95)

92% (81–96)

98% (88–99)

100% (91–100)

 PPV

79% (62–91)

79% (60–91)

76% (50–92)

89% (59–99)

100% (46–100)

 NPV

96% (84–99)

88% (76–95)

75% (62–85)

71% (59–81)

68% (57–78)

Cohort II

 Sensitivity

75% (47–92)

69% (41–88)

63% (36–84)

56% (31–79)

44% (21–69)

 Specificity

94% (68–100)

94% (68–100)

100% (76–100)

100% (76–100)

100% (76–100)

 PPV

92% (62–100)

92% (60–100)

100% (66–100)

100% (63–100)

100% (56–100)

 NPV

79% (54–93)

75% (51–90)

73% (50–88)

70% (47–86)

64% (43–81)

  1. PPV positive predictive value, NPV negative predictive value.
  2. aA cut-off value of ≥3 means that an ultrasound score of 3 or more is defined as abnormal.