Fig. 2: Relations between (log-scaled) plasma vitamin B12 status markers and age.
From: Age dependency of plasma vitamin B12 status markers in Dutch children and adolescents

Concentrations of plasma MMA (a), holoTC (b), and total Cbl (c) were log-transformed to produce 95% reference curves. The scales were log-transformed, but for clearance, concentrations are notated as non-transformed concentrations. Log plasma MMA was best described using a power fitted line (R2 = 0.189, p < 0.0001), log plasma holoTC (R2 = 0.245, p < 0.0001), and log total Cbl (R2 = 0.330, p < 0.0001)) were best described using polynomial (quartic) fitted lines.