Table 1 Baseline demographics of infants in each group.
From: Physiological dead space and alveolar ventilation in ventilated infants
Control (n = 20) | RDS (n = 35) | BPD (n = 26) | p value | |
|---|---|---|---|---|
Gestational age at birth (weeks) | 38.4 (36.7–40.2) | 29.1 (25.9–31.7) | 25.8 (25.0–27.3) | <0.001 |
Birth weight (kg) | 3.30 (2.75–3.66) | 1.00 (0.74–1.41) | 0.70 (0.58–0.82) | <0.001 |
BW Z-score | −0.07 (−0.72 to 0.63) | −0.41 (−1.56 to 0.00) | −0.76 (−1.66 to −0.19) | 0.066 |
Postnatal day of life at study (days) | 4 (2–7) | 3 (2–4) | 16 (10–25) | <0.001 |
Postmenstrual age at study (weeks) | 39.8 (37.6–40.9) | 29.6 (26.1–31.9) | 28.3 (26.9–30.2) | <0.001 |
Weight at study (kg) | 3.36 (2.85–3.78) | 1.03 (0.74–1.44) | 0.91 (0.77–1.18) | <0.001 |
End-tidal carbon dioxide (mmHg) | 31.3 (28.3–39.9) | 29.3 (24.2–33.4) | 33.7 (28.2–38.4) | 0.030 |
Mean expired carbon dioxide (mmHg) | 18.2 (15.4–21.2) | 10.6 (7.4–12.7) | 11.8 (9.9–15.1) | <0.001 |
Partial arterial pressure of carbon dioxide (mmHg) | 40.4 (34.0–43.1) | 40.0 (34.5–43.7) | 51.4 (47.8–59.0) | <0.001 |
PaCO2–EtCO2 gradient (mmHg) | 5.2 (2.8–12.2) | 10.0 (5.5–16.3) | 17.9 (14.8–27.0) | <0.001 |
Peak inspiratory pressure (cmH2O) | 18.7 (16.5–21.5) | 16.9 (13.1–20.3) | 23.8 (18.8–25.6) | 0.006 |
Positive end expiratory pressure (cmH2O) | 5.9 (5.4–6.0) | 5.4 (5.1–5.9) | 6.1 (5.4–6.7) | 0.005 |
Respiratory rate (breaths per minute) | 35 (31–39) | 45 (40–58) | 49 (42–55) | <0.001 |
