Table 2 Dead space and alveolar ventilation parameter of infants in each group.
From: Physiological dead space and alveolar ventilation in ventilated infants
Control (n = 20) | RDS (n = 35) | BPD (n = 26) | p value | Control–RDS | Control–BPD | RDS–BPD | |
|---|---|---|---|---|---|---|---|
Physiological dead space (ml/kg) | 3.5 (2.8–4.3) | 5.7 (5.1–7.0) | 6.4 (5.1–7.5) | <0.001 | <0.001 | <0.001 | 0.372 |
Total anatomical dead space (ml/kg) | 2.7 (2.4–3.2) | 5.1 (4.7–5.9) | 5.4 (4.4–6.1) | <0.001 | <0.001 | <0.001 | 0.811 |
Apparatus dead space (ml/kg) | 1.2 (1.1–1.4) | 2.8 (2.0–3.8) | 3.1 (2.8–3.7) | <0.001 | <0.001 | <0.001 | 0.353 |
Anatomical minus apparatus dead space (ml/kg) | 1.6 (1.1–2.2) | 2.4 (1.5–3.2) | 2.0 (1.4–2.9) | 0.171 | |||
Alveolar dead space (ml/kg) | 0.5 (0.3–1.2) | 0.7 (0.2–1.5) | 1.0 (0.8–1.4) | 0.018 | 0.506 | 0.006 | 0.030 |
Tidal volume (ml/kg) | 6.4 (5.4–7.6) | 8.5 (6.6–9.6) | 8.2 (7.5–10.3) | 0.009 | 0.008 | 0.004 | 0.745 |
Dead space to tidal volume ratio | 0.52 (0.43–0.62) | 0.75 (0.64–0.81) | 0.77 (0.71–0.82) | <0.001 | <0.001 | <0.001 | 0.220 |
Minute ventilation (ml/kg/min) | 239 (193–378) | 369 (311–450) | 403 (321–505) | 0.003 | 0.002 | 0.001 | 0.580 |
Alveolar ventilation (ml/kg/min) | 111 (81–159) | 83 (66–137) | 82 (62–133) | 0.537 |
