Table 3 Stratified generalized estimating equation models examining the relationship between PDA exposure and BPD or BPD/death before 36 weeks in two subpopulations of infants: those intubated for <10 days and those intubated for ≥10 days.

From: Patent ductus arteriosus, tracheal ventilation, and the risk of bronchopulmonary dysplasia

PDA duration among infants intubated <10 days

Characteristic

BPDa (N = 161)

BPD/death before 36 weeksb (N = 181)

 

OR

95% CI

P value

OR

95% CI

P value

 PDA duration

   <14 days

Ref.

  

Ref.

  

   ≥14 days

1.34

(0.87, 2.08)

0.180

1.32

(0.75, 2.29)

0.324

PDA duration among infants intubated ≥10 days

 

BPDa (N = 105)

BPD/death before 36 weeksb (N = 126)

 PDA duration

   <14 days

Ref.

  

Ref.

  

   ≥14 days

2.80

(1.31, 5.97)

0.008

2.17

(1.17, 4.02)

0.014

  1. The Final models for BPD and BPD/death were adjusted for the demographic variables from Table 1 that were considered to be “important demographic variables” (see “Methods”).
  2. aAdjusted for PDA duration, gestational age, infant still intubated at 24 h, and PDA ligation.
  3. bAdjusted for PDA duration, gestational age, infant still intubated at 24 h, PDA ligation, and intracranial hemorrhage (grades 3 or 4).
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