Table 3 Association between maternal and infant characteristics and distribution of volatile fatty acids and fatty acid esters in preterm breastmilk.

From: Odor-active volatile compounds in preterm breastmilk

Characteristics

Pentanoic acid 3-methyl

Hexanoic acid

Octanoic acid

Butanoic acid ME

Hexanoic acid ME

Octanoic acid ME

Decanoic acid ME

Dodecanoic acid ME

Lactation stage

F (3, 329.3) = 4.7**

F (3, 329.3) =  8.6***

F (3, 303.1) = 2.0, p = 0.12

F (3, 329.3) =  29.6***

F (3, 306.7) = 20.5***

F (3, 297.9) = 11.8***

F (3, 275.5) = 10.2***

F (3, 267.2) = 3.6*

ā€ƒDay 3

0 (0)AB

0 (0)A

0 (0)

0 (0)A

0 (0)A

592 (1007)AC

365 (714)A

20 (91)AB

ā€ƒDay 5

12 (91)AB

16 (912)A

423 (1213)

8 (49)A

64 (182)A

3490 (4768) B

1563 (2058)B

106 (283)A

ā€ƒDay 10

122 (465)A

46 (202)A

193 (1132)

13 (92)A

217 (402)A

1395 (2882)A

791 (1525)A

68 (213) AB

ā€ƒ4 months CA

270 (932)B

555 (1558)B

314 (672)

194 (319)B

514 (740)B

2746 (3382)BC

1153 (1345) AB

24 (92) B

Ethnicity

F (4, 157.6) =  0.42, p = 0.8

F (4, 157.7) = 1.14, p = 0.34

F (4, 160.8) = 1.4, p = 0.23

F (4, 157.6) = 0.54, p = 0.71

F (4, 160.4) = 1.3, p = 0.26

F (4, 160.9) = 3.5**

F (4, 162.9) =  4.04**

F (4, 163.6) = 1.4, p = 0.24

ā€ƒEuropean

124 (594)

262 (1142)

405 (1363)

53 (176)

251 (477)

3094 (4300) A

1486 (1907)A

93 (254)

ā€ƒMāori

95 (479)

88 (587)

87 (279)

39 (174)

183 (513)

1475 (2580)AB

678 (1115)AB

32 (103)

ā€ƒAsian

127 (564)

139 (686)

344 (1018)

61 (207)

238 (510)

2619 (3949)AB

1237 (1844)AB

85 (254)

ā€ƒPasifika

30 (230)

32 (245)

94 (459)

30 (115)

102 (280)

1281 (3021)B

469 (935)B

15 (72)

ā€ƒOther

79 (224)

0 (0)

0 (0)

0 (0)

47 (133)

291 (723)AB

144 (407)AB

0 (0)

GDM

F (1,164) = 2.52, p = 0.11

F (1,163.9) = 0.36, p = 0.55

F (1,167.8) = 2.54, p = 0.11

F (1,163.7) = 2.34, p = 0.13

F (1,166.8) = 3.14, p = 0.08

F (1,167.9) = 4.78*

F (1,169.5) = 5.9*

F (1,169.8) = 4.45*

ā€ƒNo

127 (580)

173 (898)

341 (1158)

56 (191)

235 (487)

2662 (4077)

1263 (1820)

84 (243)

ā€ƒYes

23 (124)

114 (549)

104 (357)

26 (99)

119 (359)

1463 (2606)

602 (1069)

13 (66)

NZdep

F (4, 153.1) = 1.03, p = 0.4

F (4,153.1) = 4.67**

F (4,157.4) = 4.57**

F (4,153.1) = 0.74, p = 0.57

F (4,156.9) = 2.75*

F (4,158.1) = 4.81**

F (4, 161.1) = 4.33**

F (4, 161.9) = 2.61*

ā€ƒQ1

199 (782)

127 (589)A

228 (519)A

76 (214)

294 (592)A

3076 (3672)AB

1281 (1552)AB

42 (130) AB

ā€ƒQ2

121 (611)

194 (838)A

409 (1220)AB

59 (206)

270 (527)A

2921 (4437)AB

1471 (1979)B

94 (261) AB

ā€ƒQ3

104 (354)

604 (1880)B

871 (2254)B

40 (141)

300 (574)A

4062 (5853)A

1840 (2594)B

172 (397) †A

ā€ƒQ4

36 (166)

63 (330)A

88 (273)A

45 (154)

141 (295) †B

1623 (2326)B

816 (1137)AB

39 (134) AB

ā€ƒQ5

77 (449.6)

43.7 (387.7)A

130.2 (474.7)A

34.3 (156)

123.1 (341) †B

1488 (2808)B

678 (1243)A

47 (158) †B

Antenatal steroids

F (2,153.9) = 0.21, p = 0.81

F (2,154.5) = 0.1, p = 0.9

F (2,161.4) = 0.65, p = 0.52

F (2,153.6) = 2.01, p = 0.14

F (2,160.1) = 2.53, p = 0.08

F (2,162.1) = 1.71, p = 0.18

F (2,165.2) = 2.92, p = 0.06

F (2,166.1) = 0.96, p = 0.38

ā€ƒNone

100 (443)

148 (990)

149 (579)

50 (197)

128 (378)

1571 (3379)

582 (1025)

25 (95)

ā€ƒIncomplete

142 (624)

208 (835)

360 (1027)

83 (222)

305 (608)

2638 (3972)

1295 (1844)

77 (251)

ā€ƒComplete

94 (505)

147 (798)

314 (1177)

35 (146)

200 (414)

2613 (3941)

1241 (1808)

82 (236)

Tertiary education

F (2,130.4) = 0.03, p = 0.97

F (2,131.4) = 0, p = 0.99

F (2,140.2) = 0.08, p = 0.92

F (2,130.7) = 0.02, p = 0.98

F (2,139.5) = 0, p = 0.99

F (2,142.5) = 0.36, p = 0.7

F (2,150.3) = 1.43, p = 0.24

F (2,153.2) = 0.99, p = 0.37

ā€ƒIncomplete

100 (472)

146 (836)

298 (1239)

44 (164)

207 (489)

2263 (4258)

1015 (1761)

59 (216)

ā€ƒComplete

114 (571)

176 (855)

298 (895)

55 (190)

220 (453)

2563 (3543)

1214 (1675)

76 (226)

Delivery mode

F (1,154.7) = 1.53, p = 0.22

F (1,154.6) = 2.09, p = 0.15

F (1,161.6) = 0.03, p = 0.87

F (1,154.5) = 2.8, p = 0.09

F (1,160.7) = 0, p = 0.98

F (1,162.3) = 0.13, p = 0.72

F (1,165.4) = 0.59, p = 0.44

F (1,166.3) = 0.25, p = 0.62

ā€ƒVaginal

70 (291)

234 (999)

310 (1121)

67 (217)

219 (438)

2410 (3786)

1077 (1667)

65 (216)

ā€ƒC-section

132 (639)

113 (713)

286 (1013)

38 (144)

209 (487)

2451 (3930)

1179 (1760)

74 (227)

Gestational age

F (3,152.3) = 0.76, p = 0.52

F (3,152.4) = 1.27, p = 0.29

F (3,159.2) = 0.54, p = 0.65

F (3,152.3) =  0.11, p = 0.96

F (3,158.5) = 0.1, p = 0.96

F (3,160.1) = 0.52, p = 0.67

F (3,163.3) = 0.79, p = 0.5

F (3,164.1) = 1.26, p = 0.29

ā€ƒ32

104 (563)

179 (787)

233 (583)

49 (161)

224 (526)

2293 (3576)

1013 (1527)

37 (129)

ā€ƒ33

51 (238)

170 (802)

387 (1469)

45 (160)

223 (456)

2749 (4197)

1367 (1911)

101 (258)

ā€ƒ34

136 (681)

58 (447)

240 (945)

49 (177)

189 (445)

2125 (3755)

1022 (1662)

64 (209)

ā€ƒ35

160 (506)

322 (1399)

338 (954)

63 (232)

225 (441)

2685 (3929)

1141 (1761)

82 (284)

Sex

F (1,151.7) = 0.87, p = 0.35

F (1,152.1) = 0.42, p = 0.52

F (1,158.8) = 0.03, p = 0.85

F (1,151.8) = 0.77, p = 0.38

F (1,157.8) = 0.54, p = 0.46

F (1,159.3) = 0.78, p = 0.38

F (1,162.5) = 2.08, p = 0.15

F (1,163.4) = 1.03, p = 0.31

ā€ƒMale

179 (1012)

15 (120)

303 (1233)

37 (155)

29 (261)

2124 (3850)

926 (1603)

54 (198)

ā€ƒFemale

135 (657)

28 (144)

288 (926)

57 (190)

8 (118)

2589 (3843)

1250 (1769)

80 (237)

  1. Relative peak area presented as mean (SD).
  2. ME methyl ester, GDM gestational diabetes mellitus, NZDep New Zealand Deprivation Index.
  3. Significance level is taken as p value <0.05, adjusted for comparison (Bonferroni).
  4. Different superscript letters demonstrate significant differences in relative peak area of that compoundĀ within the rowĀ category.
  5. *p  <  0.05; **p  <  0.01; ***p  <  0.001.
  6. †Adjusted p > 0.05 (Bonferroni).