Table 1 Demographic and clinical characteristics of the study group.
From: Language function following preterm birth: prediction using machine learning
Characteristics | Neonates with language composite score ≥85 (N = 75) | Neonates with language composite score <85 (N = 14) |
|---|---|---|
Antenatal | ||
 Any antenatal corticosteroids | 73 (97) | 11 (79) |
 Complete course of antenatal corticosteroids | 56 (75) | 5 (36) |
 Antenatal MgSO4 for foetal neuroprotection | 39 (52) | 8 (57) |
Perinatal | ||
Sex | ||
   Male | 35 (47) | 12 (86) |
   Female | 40 (53) | 2 (14) |
 GA (weeks) | 28.84 ± 3.28 (23.28 to 33) | 28.92 ± 2.18 (23.28 to 30.28) |
 Birth weight (g) | 1137 ± 376.5 (568 to 1500) | 1040 ± 410 (550 to 1635) |
 Birth weight z score | −0.16 ± 1.15 (−2.63 to −1.17) | 0.12 ± 1.30 (−1.77 to −1.0) |
 Apgar score at 5 min | 7.5 ± 2 (2 to 9) | 8 ± 2 (5 to 9) |
Mode of delivery | ||
   SVD | 32 (43) | 3 (21) |
   Caesarean section | 43 (57) | 11 (79) |
  Primiparity | 52 (69) | 8 (57) |
  Twin status | 21 (28) | 10 (71) |
Postnatal | ||
 BPD | 25 (33) | 6 (43) |
 LOS | 20 (27) | 5 (36) |
 NEC | 5 (7) | 0 (0) |
 ROP | 5 (7) | 1 (7) |
 Histologic chorioamnionitis | 22 (31) | 3 (21) |
 Days of intubation | 1 ± 5.5 (0 to 39) | 1 ± 1 (0 to 43) |
Feeding at discharge | ||
   Exclusive maternal breast milk | 36 (48) | 2 (14) |
   Exclusive formula or mixed feeding | 39 (52) | 12 (86) |
Demographics | ||
Maternal race | ||
   Asian | 5 (6) | 0 (0) |
   White | 66 (88) | 13 (93) |
   White/Asian | 1 (1) | 0 (0) |
   White/Black | 2 (2) | 1 (7) |
   Other mixed | 1 (1) | 0 (0) |
Maternal age (years) | 32 ± 8 (17 to 43) | 33 ± 8 (23 to 40) |
Maternal BMI | 24.7 ± 4.5 (17.4 to 43) | 24.1 ± 6.9 (18 to 30.9) |
Medical history of maternal depression | 10 (13) | 1 (7) |
Maternal education | ||
   Secondary school or below | 33 (44) | 6 (43) |
   College/University/postgraduate studies | 42 (56) | 8 (57) |
SIMD16 quintile | ||
   1 | 8 (11) | 3 (21) |
   2 | 23 (32) | 3 (21) |
   3 | 11 (15) | 3 (21) |
   4 | 12 (16) | 3 (21) |
   5 | 19 (26) | 2 (14) |
Histogram-based variables derived from DTI | ||
PSFA | 0.3 ± 0.03 (0.25 to 0.37) | 0.32 ± 0.02 (0.24 to 0.36) |
PSMD | 0.63 ± 0.07 (0.49 to 0.79) | 0.61 ± 0.07 (0.49 to 0.79) |
PSRD | 0.71 ± 0.09 (0.54 to 0.88) | 0.72 ± 0.07 (0.6 to 0.83) |
PSAD | 0.77 ± 0.08 (0.68 to 0.89) | 0.76 ± 0.09 (0.69 to 0.91) |
Bayley-III | ||
Language composite score | 100 ± 24 (86 to 132) | 77 ± 11 (56 to 83) |
