Table 3 Comparison between cases with tubular dysfunction and those without tubular dysfunction regarding urinary markers.

From: Evaluation of kidney dysfunction in childhood cancer survivors

Parameters

Total cases (No. = 52)

Test of significance

P value

 

With tubular dysfunction (No. = 25)

Without tubular dysfunction (No. = 27)

Uprotein/Cr Median (range)

Normal value up to 0.2 mg/mg

0.35 (0.25–0.46)

0.13 (0.09–0.22)

_________

<0.001**

UCa/Cr Median (range)

Normal value up to 0.22 mg/mg

0.31 (0.28–0.45)

0.16 (0.12–0.22)

_________

<0.001**

UACR (mg/g)

Normal value 2–30 mg/g

43.87 ± 17.98

31.93 ± 14.57

t-test = 3.22

0.02

UrNGAL (ng/ml)

Normal value 0.2–132

Mean ± SD

2249.3 ± 497.4

174.9 ± 33.91

t-test = 4.19

<0.001**

UrNGAL/Cr

Normal value 1.3–16.3

Mean ± SD

2990.9 ± 747.4

223.53 ± 51.76

t-test = 4.21

<0.001**

  1. *significant difference.