Table 2 Microbial diversity of maternal and environmental factors on the preterm oral microbiota.

From: Variable preterm oral microbiome stabilizes and reflects a full-term infant profile within three months

 

Overall preterm dataset

PT1 dataset

PT2 dataset

OS K-W (q value)

Faith K-W (q value)

Adonis R2 (p value)

OS K-W (q value)

Faith K-W (q value)

Adonis R2 (p value)

OS K-W (q value)

Faith K-W (q value)

Adonis R2 (p value)

DHA supplementation

0.198 (0.656)

0.252 (0.874)

0.001 (0.852)

0.513 (0.474)

0.561 (0.454)

0.018 (0.982)

1.168 (0.280)

1.023 (0.312)

0.019 (0.520)

Postnatal daya

–0.358 (0.001)

–0.354 (0.001)

0.081 (0.001)

–0.396 (0.008)

–0.406 (0.006)

0.051 (0.012)

–0.036 (0.812)

0.021 (0.892)

0.029 (0.229)

Sex

0.783 (0.376)

0.572 (0.450)

0.010 (0.458)

0.133 (0.716)

0.228 (0.633)

0.023 (0.395)

0.519 (0.023)

7.782 (0.005)

0.061 (0.009)

Singleton birth

0.826 (0.364)

0.257 (0.612)

0.007 (0.876)

1.134 (0.287)

0.954 (0.329)

0.030 (0.139)

0.548 (0.459)

0.061 (0.806)

0.012 (0.877)

Birth type (V vs C.S.)

0.851 (0.356)

1.414 (0.234)

0.026 (0.214)

0.524 (0.469)

0.380 (0.538)

0.020 (0.559)

0.002 (0.963)

0.003 (0.860)

0.015 (0.734)

Birth type (specific)

 V vs C.S. in labor

0.022 (0.639)

0.073 (0.787)

N/A

0.219 (0.639)

0.477 (0.490)

N/A

0.299 (0.676)

0.297 (0.586)

N/A

 V vs C.S. no labor

2.704 (0.150)

3.587 (0.087)

N/A

1.907 (0.250)

1.905 (0.251)

N/A

0.174 (0.676)

0.360 (0.586)

N/A

 C.S. in labor vs C.S. no labor

5.295 (0.064)

4.812 (0.085)

N/A

3.005 (0.249)

2.917 (0.251)

N/A

0.758 (0.676)

1.434 (0.586)

N/A

 Enteral feed type on discharge

0.894 (0.640)

0.282 (0.868)

0.011 (0.443)

0.142 (0.931)

0.038 (0.981)

0.038 (0.981)

0.047 (0.977)

0.001 (0.995)

0.030 (0.839)

 Probiotics

0.121 (0.728)

0.040 (0.841)

0.010 (0.458)

1.175 (0.278)

0.818 (0.178)

0.021 (0.488)

0.247 (0.619)

0.172 (0.678)

0.026 (0.307)

 Doses of antibioticsa

0.074 (0.539)

0.130 (0.278)

0.011 (0.679)

0.223 (–0.191)

0.255 (0.134)

0.026 (0.529)

–0.096 (0.576)

–0.217 (0.204)

0.039 (0.182)

 Doses of antifungalsa

–0.012 (0.920)

–0.001 (0.992)

0.008 (0.897)

0.013 (0.940)

–0.015 (0.929)

0.024 (0.675)

–0.200 (0.242)

–0.299 (0.076)

0.073 (0.006)

  1. K-W Kruskal–Wallis, q value Benjamini–Hochberg FDR-corrected p value.
  2. Bolded = q < 0.05; italics = 0.05 < q < 1.
  3. aPerformed spearman test (alpha diversity) for continuous data.
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