Table 1 Key items for framing the aim, search strategy, and study inclusion and exclusion criteria for review, in accordance with the PICOTS guidance.

From: Risk-prediction models for intravenous immunoglobulin resistance in Kawasaki disease: Risk-of-Bias Assessment using PROBAST

Item

Definition

Population

Patients diagnosed as having KD

Intervention

The model has been used since 2006/01 to 2021/05 to predict IVIG non-response in children with KD, to distinguish children with KD who show IVIG non-response, and to help clinicians to identify such patients early or make long-term treatment plan decisions

Comparator

Alternative models were not considered

Outcomes

Any clinical outcome reported by the IVIG resistance prediction models in children with KD

Timing

Before initiation of treatment with IVIG for children with KD

Setting

Patients diagnosed as showing KD in hospital or medical center/institution

  1. KD Kawasaki disease.