Table 2 Experts’ report of therapies applied during LISA.
Category | Results |
|---|---|
Report of gestational age for eligible infants, median [IQR], range | 28 [24–32], 22–42 |
Report of analgesic/sedative pharmacological treatment, n (%)a | |
Fentanyl | 75 (49%) |
Propofol | 28 (18%) |
Ketamine | 17 (11%) |
Lidocain spray | 2 (1%) |
Midazolam | 7 (5%) |
Phenobarbital | 2 (1%) |
Morphine | 7 (5%) |
Sufentanil | 1 (1%) |
No use of analgesics/sedatives | 63 (41%) |
Report of non-pharmacological treatment, n (%)a | |
Swaddling/wrapping | 89 (58%) |
Sucrose | 73 (48%) |
Tucking | 70 (46%) |
Skin-to-skin care | 23 (15%) |
Environment (light and noise reduction) | 19 (12%) |
Containment/holding | 15 (10%) |
Positioning | 10 (7%) |
Non-nutritive suctioning | 6 (4%) |
NIDCAP principles | 3 (2%) |
Human milk | 3 (2%) |
No use of non-pharmacological treatment | 6 (4%) |
Report of surfactant used, n (%) | |
Curosurf/Poractant alfa/Porcine surfactant | 125 (94%) |
Calsurf/Bovine surfactant | 8 (6%) |
Report of pre-procedure pharmacological treatment, n (%)a | |
Caffeine | 138 (90%) |
Atropine | 35 (23%) |
Paracetamol | 2 (1%) |
No use of pre-procedure pharmacological treatment | 11 (7%) |
Report of post-procedure pharmacological treatment, n (%)a | |
Naloxone | 36 (24%) |
Caffeine | 7 (5%) |
Theophylline | 1 (1%) |
Paracetamol | 1 (1%) |
Antibiotics | 1 (1%) |
Atropine | 1 (1%) |
Doxapram | 1 (1%) |
No use of post-procedure pharmacological treatment | 106 (69%) |
Report of respiratory support during LISA, n (%)a | |
nCPAP | 129 (84%) |
NIPPV | 71 (46%) |
HFNC | 14 (9%) |
Other respiratory support during LISA | 9 (6%) |