Fig. 5: Relationship between the optical indices of cerebral metabolic and cerebrovascular dysfunction with Lac/NAA and TUNEL cell count. | Pediatric Research

Fig. 5: Relationship between the optical indices of cerebral metabolic and cerebrovascular dysfunction with Lac/NAA and TUNEL cell count.

From: Early assessment of injury with optical markers in a piglet model of neonatal encephalopathy

Fig. 5: Relationship between the optical indices of cerebral metabolic and cerebrovascular dysfunction with Lac/NAA and TUNEL cell count.

Linear regression analysis for cerebrovascular dysfunction index BFI-HbD semblance (a–c) and metabolic dysfunction index oxCCO-HbD semblance (d–f). BFI-HbD semblance correlated significantly with a BGT logLac/NAA (r2 = 0.46, p = 0.004), b WM logLac/NAA (r2 = 0.45, p = 0.004) and c Thalamic TUNEL cell count (r2 = 0.34, p = 0.02). oxCCO-HbD semblance correlated significantly with d BGT logLac/NAA (r2 = 0.34, p = 0.01) and e WM logLac/NAA (r2 = 0.46, p = 0.002) but not with f Thalamic TUNEL cell count (r2 = 0.17, p = 0.09).

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