Fig. 6: Differentially expressed genes (DEGs) in BAC-treated and control mice, and comparison with DEGs in dilated and narrowed segments in HSCR patients. | Pediatric Research

Fig. 6: Differentially expressed genes (DEGs) in BAC-treated and control mice, and comparison with DEGs in dilated and narrowed segments in HSCR patients.

From: Establishment and identification of an animal model of Hirschsprung disease in suckling mice

Fig. 6: Differentially expressed genes (DEGs) in BAC-treated and control mice, and comparison with DEGs in dilated and narrowed segments in HSCR patients.

a Volcano plot of DEGs from BAC-treated and control mice. Dots in green indicates the genes with low expression, and red indicates the genes with high expression. The dots marked with dark colors represent the genes associated with HSCR, which are listed on either side of the volcano plot. b Venn diagram of overlapped DEGs in HSCR patients (Blue) and mouse model (Orange). c GO Term analysis on biological processes of overlapped DEGs in HSCR patients and mouse models.

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