Fig. 4: In vitro protective effect of Tie2 mAb against damage to vascular endothelial cells.
From: Reduction of renal interstitial fibrosis by targeting Tie2 in vascular endothelial cells
a mRNA levels of VCAM-1 and (b) Bax were detected by quantitative PCR. c Protein expression level of α-SMA in HUVECs was assessed by western blotting. d Densitometric analyses were presented as the relative ratio of α-SMA to β-actin. All data are expressed as mean ± SD (n = 6). *p < 0.05, **p < 0.01, ***p < 0.001. VCAM-1 vascular cell adhesion molecule-1, Bax Bcl-2-associated X protein, α-SMA α-smooth muscle actin, HUVECs human umbilical vein endothelial cells.
