Table 4 Results of Model 4. Effect of postmenstrual age, study group, systemic-to-pulmonary shunt, aortic arch obstruction and oxygen saturation on cerebral perfusion in deep and cortical gray matter.

From: Effects of hemodynamic alterations and oxygen saturation on cerebral perfusion in congenital heart disease

 

Beta

95% CI

p value

Perfusion in deep Gray Matter

 Intercept

−8.47

−41.60–24.88

0.63

 Postmenstrual age, weeks

1.16

0.53 – 1.81

<0.001*

 Systemic-to-pulmonary shunt: yes

−3.84

−7.50–−0.40

0.024*

 Aortic arch obstruction: yes

4.23

−0.67–9.55

0.06

 O2 Saturation, %

−0.17

−0.40–0.07

0.16

 Study group: CHD

3.57

0.75–6.37

0.018*

Perfusion in cortical Gray Matter

 Intercept

1.02

−18.64–20.69

0.92

 Postmenstrual age, weeks

0.70

0.33–1.07

<0.001*

 Systemic-to-pulmonary shunt: yes

−3.37

−5.31–−1.44

0.001*

 Aortic arch obstruction: yes

0.68

−1.95–3.32

0.62

 O2 Saturation, %

−0.11

−0.25–0.03

0.12

 Study group: CHD

2.29

0.60–3.98

0.012*

  1. CHD congenital heart disease, CI confidence interval, O2 oxygen.
  2. *p < Bonferroni-corrected alpha significance level 0.025.
  3. Patients with pulmonary-to-systemic shunt (n = 3) or common arterial trunk (n = 1) were excluded from analysis in Model 4.
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