Table 2 Comparison of maternal and neonatal characteristics of infants with different severity of BPD—Jensen 2019 definition (N = 227).

From: Impact of severity and age with variable definitions of bronchopulmonary dysplasia on neurodevelopmental outcomes

 

Jensen 2019—No BPD (N = 141)

Jensen 2019—Grade 1 BPD (N = 63)

Jensen 2019—Grade 2/3 BPD (N = 23)

P value

Maternal characteristics

Antenatal Steroids (≥2 doses)

130 (92.2%)

59 (93.7%)

20 (87.0%)

0.594

Cesarean Section

64 (45.4%)

39 (61.9%)

15 (65.2%)

0.038

Chorioamnionitis

16 (11.3%)

9 (14.3%)

0 (0.0%)

0.169

Maternal Diabetes

19 (13.5%)

8 (12.9%)

4 (17.4%)

0.859

PIH or Pre-eclampsia

56 (39.7%)

23 (36.5%)

6 (26.1%)

0.449

Neonatal Characteristics

Birth Weight (grams) (±SD)

1079.40 (231.28)

885.21 (219.94)

728.96 (193.38)

<0.001

Gestational Age (weeks) (±SD)

28.81 (2.03)

27.13 (2.11)

25.81 (1.67)

<0.001

Race

   White

41 (29.1%)

23 (36.5%)

3 (12.5%)

 

   Black

60 (42.6%)

22 (34.9%)

14 (58.3%)

0.218

   Hispanic

30 (21.3%)

16 (25.4%)

4 (16.7%)

 

   Other

10 (7.1%)

2 (3.2%)

3 (13.0%)

 

Male Sex

69 (48.9%)

34 (54.0%)

15 (65.2%)

0.327

SGA

20 (14.2%)

9 (14.8%)

3 (13.0%)

0.980

Delivery Room Intubation

60 (42.6%)

43 (68.3%)

22 (95.7%)

<0.001

Surfactant use

61 (43.3%)

50 (79.4%)

23 (100%)

<0.001

Days of Mechanical Ventilation (IQR)

0 (0-2)

9 (2-28.5)

42 (16-52)

<0.001

PDA requiring treatment

10 (7.1%)

17 (27.0%)

11 (47.8%)

<0.001

IVH ≥ Grade 3

11 (7.8%)

5 (7.9%)

4 (17.4%)

0.309

Culture Positive Sepsis

69 (48.9%)

42 (66.7%)

17 (73.9%)

0.013

NEC ≥ Stage 2

4 (2.8%)

2 (3.2%)

5 (21.7%)

≤0.001

Cystic PVL

11 (7.8%)

4 (6.3%)

3 (12.5%)

0.612

ROP requiring treatment

0 (0.0%)

9 (14.3%)

6 (26.1%)

<0.001

Postnatal Steroids

9 (6.4%)

23 (36.5%)

16 (69.6%)

<0.001

  1. The p value listed for each variable compared no BPD to each specific severity of BPD.
  2. BPD bronchopulmonary dysplasia, IQR interquartile range, IVH intraventricular hemorrhage, NEC necrotizing enterocolitis, PDA patent ductus arteriosus, PIH pregnancy-induced hypertension, PVL periventricular leukomalacia, ROP retinopathy of prematurity, SD standard deviation, SGA small for gestational age.